So, I just got my EnteroLab results back and surprisingly wasn't sensitive to ANY of the four things tested!?
Gluten-7 units
Casein-2 units
Eggs-2 units
Soy-1 unit
I know that raw veggies and lactose producing things can cause me gas problems. But, now I am back at square one (but, pretty happy with the results) as far as which direction to go? I haven't had any diarrhea for over 3 months. I just struggle at times with bloating and gas. Should I still stay off of gluten, even with these results? I will start being more consistent with my food diary.
Thanks Tex and any input from anyone else would be greatly appreciated!
EnteroLab Results
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Hi Marty,
Since all of your antibody scores were pretty low, that suggests that you might have selective IgA deficiency (approximately 1 in every 500 people in the general population have selective IgA deficiency, and at least 1 in every 300 people who are sensitive to gluten have the disorder).
Just to be on the safe side, it might be a good idea to ask your doctor to check you for selective IgA deficiency. And just in case you have it, it might be prudent to continue the diet at least until you have a confirmation that you do not have it. If you do have selective IgA deficiency, you are in good company, because other members here also have the problem. Selective IgA deficiency means that the body does not produce normal amounts if immunoglobulin A, and when that is the case, all ELISA-based tests will show false negative results. That includes the stool tests that EnteroLab uses, and it also includes the blood tests that all doctors use to screen for celiac disease. And it means that your immune system cannot produce a normal response to most vaccinations (IOW, most vaccines will probably not prompt your immune system to develop an immunity).
On the other hand, if you already have been tested, and you know that you do not have selective IgA deficiency, then you might not be sensitive to any or all of those foods. The big question is, "Why are you in remission?" If it is because of the diet changes, then you may need to experiment to find out which foods are the problem, before reverting back to your old original diet. The most likely culprits are gluten and dairy, but that's just a guess based on statistics. The first step will be to verify whether or not you immunoblobulin A levels are normal.
Do you mind if I add your results to our list?
Tex
Since all of your antibody scores were pretty low, that suggests that you might have selective IgA deficiency (approximately 1 in every 500 people in the general population have selective IgA deficiency, and at least 1 in every 300 people who are sensitive to gluten have the disorder).
Just to be on the safe side, it might be a good idea to ask your doctor to check you for selective IgA deficiency. And just in case you have it, it might be prudent to continue the diet at least until you have a confirmation that you do not have it. If you do have selective IgA deficiency, you are in good company, because other members here also have the problem. Selective IgA deficiency means that the body does not produce normal amounts if immunoglobulin A, and when that is the case, all ELISA-based tests will show false negative results. That includes the stool tests that EnteroLab uses, and it also includes the blood tests that all doctors use to screen for celiac disease. And it means that your immune system cannot produce a normal response to most vaccinations (IOW, most vaccines will probably not prompt your immune system to develop an immunity).
On the other hand, if you already have been tested, and you know that you do not have selective IgA deficiency, then you might not be sensitive to any or all of those foods. The big question is, "Why are you in remission?" If it is because of the diet changes, then you may need to experiment to find out which foods are the problem, before reverting back to your old original diet. The most likely culprits are gluten and dairy, but that's just a guess based on statistics. The first step will be to verify whether or not you immunoblobulin A levels are normal.
Do you mind if I add your results to our list?
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Sure you are welcome to add my results! I called my doctor and also a local blood lab and no one seems to know what I am talking about with testing for a selective IgA deficiency! =/ Is there something else to call it or do you know if there are labs like EneroLab that does that sort of thing?
Thanks!
Thanks!
That's almost unbelievable.Marty wrote:no one seems to know what I am talking about with testing for a selective IgA deficiency!
Apparently knowledge of the immune system isn't your doctor's strong suit. 
Here is a link to an article that tells you everything you (and your doctor) need to know about Selective Iga deficiency:
http://www.info4pi.org/aboutPI/index.cf ... TOKEN=3244Confirmation of Selective IgA Deficiency is made though a laboratory test which measures IgA levels in the blood or serum. In the IgA-deficient patient, IgA levels will either be absent or below 7mg/dl, while other classes of immunoglobulin are normal. In a small percentage of cases, perhaps 10%, an IgA-deficient patient may also be deficient in IgG2. T-cells, phagocytic cells, and the complement system are normal or near normal.
It's possible that there may be independent labs that will do that test direct to patients, but I'm not familiar with them (if they exist).
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
My IgA results
Tex,
Can you help me out? I got my IgA tested and got these results back.
I don't know what they mean??
It was a test for Immunoglobin A
Results...
Out of Range (65L)
Reference Range (81-463 mg/dL)
Thanks so much!
Marty
Can you help me out? I got my IgA tested and got these results back.
I don't know what they mean??
It was a test for Immunoglobin A
Results...
Out of Range (65L)
Reference Range (81-463 mg/dL)
Thanks so much!
Marty
Hi Marty,
I agree with Donna. According to the lab's reference range for that particular test, your result is definitely below the normal range. Therefore you apparently have selective IgA deficiency.
That means that not only will the EnteroLab results on their tests that are based on IgA antibodies be inaccurate (they will probably produce false negative results), but the celiac blood tests that your doctors may have used to screen for celiac disease, will also be unreliable, and may produce false negative results.
The result of 7 that you mentioned is associated with a completely different test. You are probably referring to the test that your doctor used to screen for anti-gliadin antibodies in your blood, to look for celiac disease. But a negative result on that that test is worthless, since you have selective IgA deficiency.
Tex
I agree with Donna. According to the lab's reference range for that particular test, your result is definitely below the normal range. Therefore you apparently have selective IgA deficiency.
That means that not only will the EnteroLab results on their tests that are based on IgA antibodies be inaccurate (they will probably produce false negative results), but the celiac blood tests that your doctors may have used to screen for celiac disease, will also be unreliable, and may produce false negative results.
The result of 7 that you mentioned is associated with a completely different test. You are probably referring to the test that your doctor used to screen for anti-gliadin antibodies in your blood, to look for celiac disease. But a negative result on that that test is worthless, since you have selective IgA deficiency.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Thanks Tex!
I actually got that "7" from you =) (along with different sites online).
See comment below (from you)...
That's almost unbelievable. Shocked Apparently knowledge of the immune system isn't your doctor's strong suit. Laughing
Here is a link to an article that tells you everything you (and your doctor) need to know about Selective Iga deficiency:
Quote:
Confirmation of Selective IgA Deficiency is made though a laboratory test which measures IgA levels in the blood or serum. In the IgA-deficient patient, IgA levels will either be absent or below 7mg/dl
I don't want to seem high maintenance or difficult! If I am IgA deficient, I can work with that. I just want to know what I'm really looking at with my body!
Thanks so much!
I actually got that "7" from you =) (along with different sites online).
See comment below (from you)...
That's almost unbelievable. Shocked Apparently knowledge of the immune system isn't your doctor's strong suit. Laughing
Here is a link to an article that tells you everything you (and your doctor) need to know about Selective Iga deficiency:
Quote:
Confirmation of Selective IgA Deficiency is made though a laboratory test which measures IgA levels in the blood or serum. In the IgA-deficient patient, IgA levels will either be absent or below 7mg/dl
I don't want to seem high maintenance or difficult! If I am IgA deficient, I can work with that. I just want to know what I'm really looking at with my body!
Thanks so much!
Marty,
Every lab has it's own "normal" range for all test parameters, and those ranges depend on the type of testing procedure that they use, and the calibration of the testing equipment. I don't recall which lab I might have been referring to, that had a minimum test threshold of "7", but clearly your result was below the normal range for the particular lab test that you used.
Without a lab's normal reference range, many test results are meaningless.
You're very welcome,
Tex
Every lab has it's own "normal" range for all test parameters, and those ranges depend on the type of testing procedure that they use, and the calibration of the testing equipment. I don't recall which lab I might have been referring to, that had a minimum test threshold of "7", but clearly your result was below the normal range for the particular lab test that you used.
Without a lab's normal reference range, many test results are meaningless.
You're very welcome,
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.