Tex? Diet Affects Autoinflammatory Disease Via Gut Microbes
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Tex? Diet Affects Autoinflammatory Disease Via Gut Microbes
Tex, what do you make of this? Thanks
MC diagnosed 2007
Hi,
I read that article a while back, but shrugged it off as old news. I can't see that they "discovered" anything that wasn't already known. It's been known for a few years that gut bacteria (and many other things, such as vitamin D, stress, epigenetics (stress or other environmental influences experienced by our parents and/or grandparents), etc., can alter our gene expression. And obviously gene expression has a huge influence on not only the risk of developing AI diseases, but the actual development of AI diseases, and the way that they develop (the actual mechanism by which it occurs in specific cases, for example).
Anytime we change our diet in any way, we alter our gut bacteria balance, sometimes slightly, sometimes grossly, depending on the details of the changes and other environmental influences.
So yes, diet can affect the development of AI diseases. But we've always known that on this board, because we've noticed by our own experiences that correcting diet problems helps to prevent the development of additional AI diseases, and even eliminates symptoms for some AI diseases that have already developed, in many cases. By comparison, the controls (everyone else in the general population who do not correct their diet, but rely on drugs instead) continue to development higher numbers of, and more severe degrees of additional AI diseases, because they never stop the inflammation that is promoting those AI diseases (the drugs only partially attenuate the inflammation).
That doesn't mean that by altering our diet we are absolutely immune to additional AI disease development (anymore than stopping a smoking habit makes us immune to lung cancer), because it's possible that the genes that predispose to those AI diseases may have been triggered before we corrected our diet. But it certainly means that the sooner we correct our diet the less likely we are to develop additional AI diseases.
Tex
I read that article a while back, but shrugged it off as old news. I can't see that they "discovered" anything that wasn't already known. It's been known for a few years that gut bacteria (and many other things, such as vitamin D, stress, epigenetics (stress or other environmental influences experienced by our parents and/or grandparents), etc., can alter our gene expression. And obviously gene expression has a huge influence on not only the risk of developing AI diseases, but the actual development of AI diseases, and the way that they develop (the actual mechanism by which it occurs in specific cases, for example).
Anytime we change our diet in any way, we alter our gut bacteria balance, sometimes slightly, sometimes grossly, depending on the details of the changes and other environmental influences.
So yes, diet can affect the development of AI diseases. But we've always known that on this board, because we've noticed by our own experiences that correcting diet problems helps to prevent the development of additional AI diseases, and even eliminates symptoms for some AI diseases that have already developed, in many cases. By comparison, the controls (everyone else in the general population who do not correct their diet, but rely on drugs instead) continue to development higher numbers of, and more severe degrees of additional AI diseases, because they never stop the inflammation that is promoting those AI diseases (the drugs only partially attenuate the inflammation).
That doesn't mean that by altering our diet we are absolutely immune to additional AI disease development (anymore than stopping a smoking habit makes us immune to lung cancer), because it's possible that the genes that predispose to those AI diseases may have been triggered before we corrected our diet. But it certainly means that the sooner we correct our diet the less likely we are to develop additional AI diseases.
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Yes, in the experiment, a diet rich in saturated fats and cholesterol protected the mice from the bone and joint problems that they were genetically inclined to develop. This is why people who have RA, Alzheimer's, and various other AI issues shouldn't be taking statins or following a low-fat diet (because they're counterproductive), IMO.
Tex
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
It just occurred to me that the improvement I have had in joint pain, muscle pain, and brain fog might be partly due to increased fat intake (butter & coconut oil) and stopping the statins. I had attributed it to my restrictive diet GF, SF, EF, DF.tex wrote:Yes, in the experiment, a diet rich in saturated fats and cholesterol protected the mice from the bone and joint problems that they were genetically inclined to develop. This is why people who have RA, Alzheimer's, and various other AI issues shouldn't be taking statins or following a low-fat diet (because they're counterproductive), IMO.
Tex
Theresa
MC and UC 2014
in remission since June 1, 2014
We must all suffer one of two things: the pain of discipline or the pain of regret. ~Jim Rohn
MC and UC 2014
in remission since June 1, 2014
We must all suffer one of two things: the pain of discipline or the pain of regret. ~Jim Rohn
Theresa,
IMO, they are both important. The diet changes stop the leaky gut from allowing peptides to leak out and be deposited in joints and muscles (to cause inflammation) at various locations in the body (including the brain, because gluten peptides can cross the blood/brain barrier), and the increased fat intake helps to keep moving parts and the myelin sheaths that protect nerve fibers, lubricated and protected from drying out. Adequate fatty acids are vital to prevent premature aging. IMO adequate fat in the diet is important not only for longevity, but also for improved quality of life (as we get older).
Tex
IMO, they are both important. The diet changes stop the leaky gut from allowing peptides to leak out and be deposited in joints and muscles (to cause inflammation) at various locations in the body (including the brain, because gluten peptides can cross the blood/brain barrier), and the increased fat intake helps to keep moving parts and the myelin sheaths that protect nerve fibers, lubricated and protected from drying out. Adequate fatty acids are vital to prevent premature aging. IMO adequate fat in the diet is important not only for longevity, but also for improved quality of life (as we get older).
Tex
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
We were on the 20/20 diet before dx. 20+ grams fiber and 20- grams fat.
After the initial weight loss I started increasing my calories and fat and of course low fiber is a must.
My DH eats pretty much the same diet I have and he has noticed less joint problems, etc. He still keeps a loaf of bread for sandwiches at lunch.
We had our Christmas celebration yesterday. Ham, sweet potato casserole and green beans. He had 2 brown & serve rolls. Vegan pumpkin bread & coconut candies. We snacked on leftovers and watched old movies on TV all day!
Today I am traveling about 4 hours to spend a few days with my daughter and her family. She has been downloading recipes and asking me what I can eat, so nice of her to plan menus around me. I told her not to worry I will bring a few standby foods and it will be fine. Also I am still on the Uceris until January 6th so a little cross contamination will probably be ok.
After the initial weight loss I started increasing my calories and fat and of course low fiber is a must.
My DH eats pretty much the same diet I have and he has noticed less joint problems, etc. He still keeps a loaf of bread for sandwiches at lunch.
We had our Christmas celebration yesterday. Ham, sweet potato casserole and green beans. He had 2 brown & serve rolls. Vegan pumpkin bread & coconut candies. We snacked on leftovers and watched old movies on TV all day!
Today I am traveling about 4 hours to spend a few days with my daughter and her family. She has been downloading recipes and asking me what I can eat, so nice of her to plan menus around me. I told her not to worry I will bring a few standby foods and it will be fine. Also I am still on the Uceris until January 6th so a little cross contamination will probably be ok.
Theresa
MC and UC 2014
in remission since June 1, 2014
We must all suffer one of two things: the pain of discipline or the pain of regret. ~Jim Rohn
MC and UC 2014
in remission since June 1, 2014
We must all suffer one of two things: the pain of discipline or the pain of regret. ~Jim Rohn