Hi Polly,
Do you happen to know how long a patient needs to be off of Geodon before beginning some of the antibiotics that are contraindicated with it?
We've been having a heck of a time getting Mom's dosage past 20 mg due to having to take her off for one reason or the other, and NOW, her painful great toe has developed a full blown infection. Guess this was in the works for a good while, and not sure whether the resent fall might've aggravated it or not. Kinda think it's just a coincidence.
Anyway, Cipro's about the only antibiotic that probably wouldn't be a problem without the Geodon being removed, but it wouldn't get every possible bug. Unfortunately, we've got to watch the prolonged cardiac intervals with some of the other choices, or else she's allergic to them. Thus, we think we'll need to take her back off the Geodon. When we do that, it's liable to get pretty wild around here, but perhaps she won't feel up to running from the hallucinations now.
She's been sleeping lots, but when aroused, she's been able to eat normally, and just about at the same level she was before the fall which was a bit decreased recently anyway, so it's kind of confusing assessing her status with more than one thing going on.
Another thing that might've made her more lethargic was that I gave her a dose with her evening meal last night, rather than at noon. It may still knock her out a little, and think it peaks in about 6 hours, so could be that sleeping late was just because it hadn't yet worn off.
It's possible that all the trauma, plus possibly having a temp elevation, and perhaps being a bit dehydrated, that that, in and of itself may be making her want to sleep when she's not eating, etc.
I'm watching her very closely which I do constantly anyway, just in case she develops any indication that a subdural might be possible. I dread the thought of her having to have a hole drilled in her head, but if it's necessary, guess that would be better than the alternative.
Hate to not start the antibiotic immediately, but then perhaps it will be ok to take it soon since she hasn't had any since late afternoon yesterday, I believe.
I'm also wondering if perhaps her knee's not trying to give out on that side. Could be that having those badly damaged tendons in her ankles for all this time (since a fall in '93), even though she hasn't walked all that much especially in the last few years, could've gradually worn something out. Just don't see how she could walk with her foot turning out like it is now (even worse angle) without damaging the structures higher up the leg -- thus the knee theory. Wow, this is something I need to discuss with Sis, and then somehow get her to the orthopedic guy.
We already have an appointment with her internist for Wed. so that Sis can help me get her there to follow up on the antibiotics.
Sure do hope that she doesn't get another allergic reaction to that! Last antibiotic she was on, prior to starting this neuroleptic, she got a little bit of a rash toward the end. Hmm, wonder if she really couldn't use that one again? When I was tested for antibiotics by an allergist back in 02, he told me that I didn't react to any of the INJECTIBLE forms, even to the cephalosporin that had swelled my lips big time in the long acting oral form. This doc said that one day you can be allergic, and another day not, so this makes me wonder how come we do the testing in the first place. Hmm, for one reason, cause I asked him to do it! Ha!
Allergist said that he would reserve the cephalosporins for last due to the reaction to that oral form anyway. Problem is that, as happened when I appeared to need an antibiotic after thyroid surgery, the alternatives to cephalosporins are the same ones that get one a nice case of C-diff.
Do many people have all these "option" problems with medications? Do you think that some of these reactions to oral forms are really reactions to the fillers and not the active drug itself? Seems like swelling lips would be kind of extreme for just a filler? What planet do these fillers come from, anyway?
Welp, think I got way off my original subject for this post...sorry!
Better get off here in case anyone trys to call here. Thanks!
Yours, Luce
Polly re: Geodon and antibiotics
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Hi Luce,
I wouldn't be jumping in here, except that Polly has been AWOL since 9:17 yeasterday morning. For all I know, she may be taking a trip over the weekend, so it may be several days before she sees your post, (if she sees it at all).
I know nothing about Geodon, other than what is posted to the www. All the sources that I could find, that discuss medications that might interact with Geodon, seem to be quoting, (or plagiarizing), the same source, and that source just says to not take Geodon with the listed antibiotics.
I take that to mean that a separation of a few hours should be sufficient. Normally, when a withdrawal period of a day or more is required, the details are specifically spelled out on the label. Here's a site that "might" be the primary source for that information:
http://www.drugdigest.org/DD/DVH/Uses/0 ... on,00.html
A phone call to your doctor or pharmacist would probably provide a quick answer, if there's any doubt in your mind.
Wayne
I wouldn't be jumping in here, except that Polly has been AWOL since 9:17 yeasterday morning. For all I know, she may be taking a trip over the weekend, so it may be several days before she sees your post, (if she sees it at all).
I know nothing about Geodon, other than what is posted to the www. All the sources that I could find, that discuss medications that might interact with Geodon, seem to be quoting, (or plagiarizing), the same source, and that source just says to not take Geodon with the listed antibiotics.
I take that to mean that a separation of a few hours should be sufficient. Normally, when a withdrawal period of a day or more is required, the details are specifically spelled out on the label. Here's a site that "might" be the primary source for that information:
http://www.drugdigest.org/DD/DVH/Uses/0 ... on,00.html
A phone call to your doctor or pharmacist would probably provide a quick answer, if there's any doubt in your mind.
Wayne
It is suspected that some of the hardest material known to science can be found in the skulls of GI specialists who insist that diet has nothing to do with the treatment of microscopic colitis.
Hi Luce and Wayne,
I think the half life is about 7 hours, so I would imagine that it would be out of the body fairly quickly. It is metabolized in the liver primarily. Of course, in someone with liver damage or even in an elderly person, metabolism can be impaired, and it could take longer. I would think that a psychiatrist would have the best info......of course the pharmacist is a good idea too, as well as her own doc.
I think it is wise to pay very close attention to the toe infection. Hope it improves soon.
Love,
Polly
I think the half life is about 7 hours, so I would imagine that it would be out of the body fairly quickly. It is metabolized in the liver primarily. Of course, in someone with liver damage or even in an elderly person, metabolism can be impaired, and it could take longer. I would think that a psychiatrist would have the best info......of course the pharmacist is a good idea too, as well as her own doc.
I think it is wise to pay very close attention to the toe infection. Hope it improves soon.
Love,
Polly
Blessed are they who can laugh at themselves, for they shall never cease to be amused.