What genes do you have DQ2 or DQ8 or other?

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mle_ii
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What genes do you have DQ2 or DQ8 or other?

Post by mle_ii »

I'm curious about those here who have been tested for the gluten sensitivity genes. Doesn't matter what lab. Please list what you have. Also, please list both genes. I'll compile in this first post starting with me.

HLA-DQ2
mle

HLA-DQ3

HLA-DQ4

HLA-DQ1 subtype DQ5

HLA-DQ1 subtype DQ6

HLA-DQ3 subtype DQ7
mle

HLA-DQ3 subtype DQ8

HLA-DQ3 subtype DQ9

Entries
mle_ii HLA-DQB1*0201, 0301

Here's some info if you need to translate your lab results:
Interpretation Of HLA-DQ Testing by Molecular Analysis and Conversion to "Serologic Equivalent": Today HLA-DQ gene testing is done by analyzing DNA using molecular techniques. In the past, the methods were done by analyzing blood cells for the antigens produced by the genes, and these past methods were responsible for the most commonly known nomenclature for HLA-DQ genes even today (using integers such as "DQ2"). These are called "serologic equivalents" to the specifically analyzed gene material. The serologic equivalents are as follows:

* If the first two numbers of the molecular type are 05, the serologic equivalent is DQ1 subtype DQ5
* If the first two numbers of the molecular type are 06, the serologic equivalent is DQ1 subtype DQ6
* If the molecular type is 0201, the serologic equivalent is DQ2
* If the molecular type is 0301, the serologic equivalent is DQ3 subtype DQ7
* If the molecular type is 0302, the serologic equivalent is DQ3 subtype DQ8
* If the molecular type is 0303, the serologic equivalent is DQ3 subtype DQ9
* If the first two numbers of the molecular type are 03 but it is not 0301, 0302, or 0303, the serologic equivalent is DQ3
* If the first two numbers of the molecular type are 04, the serologic equivalent is DQ4

The gluten sensitive, celiac genes are HLA-DQB1*0201 and HLA-DQB1*0302 (HLA-DQ2 and HLA-DQ8, respectively).

The other gluten sensitive genes are any molecular type involving another HLA-DQB1*03 number (i.e., HLA-DQ3), or any HLA-DQB1*05 number, or any HLA-DQB1*06 number (i.e., HLA-DQ1)
mle_ii
Rockhopper Penguin
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Posts: 1487
Joined: Wed May 25, 2005 5:29 pm
Location: Seattle, WA

Post by mle_ii »

Ah, I see we already did this here:
http://www.perskyfarms.com/phpBB2/viewtopic.php?t=2645
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