For those of us who have been following Dr. Fasano's progress in developing and testing a pill to counter zolulin, and thereby keep the "tight junctions" in the epithelia of the intestines closed, here's a recent report with news that the project is still on track:
http://www.medicalnewstoday.com/articles/124585.php
Also, note the phrase from that report, suggesting that the product, larazotide acetate, (AT-1001), may also be useful as a treatment for IBDs. How about that?
If you want some background information on the theory involved, and the company that he co-founded to develop and market the product, here's an article from a couple of years ago:Results from a second poster presented at ACG showed that larazotide acetate also inhibited the effect of inflammatory cytokines, including tumor necrosis factor (TNF-alpha) and interleukin (IL-4) on intestinal epithelial permeability, in vitro, further suggesting that the product offers potential as a future treatment for inflammatory bowel disease (IBD).
http://www.albatherapeutics.com/Default.aspx?tabid=178
When this product finally receives FDA approval, and hits the market, it will probably be the closest thing to "magic" that we will ever see in our lifetimes.
Tex